Pomegranate Peel Extract Supplement

Ciyuan®- Your Trusted Supplier of Pomegranate Peel Extract Supplement

Pomegranate peel extract supplement is a concentrated form of bioactive compounds derived from the dried peel of the pomegranate fruit (Punica granatum). The peel, which constitutes approximately 50% of the fruit’s weight, is rich in phytochemicals that are often present in higher concentrations than in the fruit’s juice or seeds.​

To create the supplement, pomegranate peels are first cleaned, dried, and processed into a fine powder. This powder may undergo further extraction using water, ethanol, or other solvents to isolate and concentrate key compounds like polyphenols, ellagitannins, and flavonoids. The resulting extract is then formulated into various forms, including capsules, tablets, or liquid tinctures, making it easy to incorporate into daily routines.​

Unlike fresh pomegranate peel, which is bitter and tough to consume, the supplement provides a convenient way to access the peel’s beneficial components without the unpleasant taste. It is widely available in health food stores, online marketplaces, and through supplement retailers, often marketed as a natural support for immune health, digestion, and overall wellness.​

COA

Composition:

Key Compounds in Pomegranate Peel Extract​

The immune-supporting potential of pomegranate peel extract lies in its rich array of bioactive compounds. These include:​

• Ellagitannins: A type of polyphenol, ellagitannins are among the most abundant compounds in pomegranate peel. In the body, they are converted into ellagic acid and urolithins, which exhibit strong antioxidant and anti-inflammatory properties.​

• Flavonoids: Compounds like quercetin, kaempferol, and anthocyanins are present in pomegranate peel, contributing to its antioxidant capacity and supporting immune cell function.​

• Tannins: These astringent compounds help protect the body from oxidative stress and may support the integrity of mucosal barriers, such as those in the gut and respiratory tract—key frontlines of the immune system.​

• Vitamins and Minerals: Pomegranate peel contains small amounts of vitamin C, vitamin E, and minerals like zinc and selenium, all of which play roles in immune function.​

Together, these compounds work synergistically to support various aspects of immune health, from enhancing cellular defenses to reducing oxidative damage.​

How Pomegranate Peel Extract May Support Immune Function​

1. Enhances Antioxidant Defense​

Oxidative stress, caused by an imbalance between free radicals and antioxidants in the body, can weaken the immune system by damaging immune cells and impairing their function. Pomegranate peel extract is a potent source of antioxidants, which neutralize free radicals and reduce oxidative stress.​

Ellagitannins, in particular, have been shown to have a higher antioxidant capacity than many other plant compounds. By scavenging free radicals, they protect immune cells—such as lymphocytes and macrophages—from damage, ensuring these cells can effectively identify and eliminate harmful pathogens. Additionally, antioxidants in the extract support the production of glutathione, a key antioxidant produced by the body that is critical for immune cell function.​

By reducing oxidative stress, pomegranate peel extract helps create an environment where the immune system can operate optimally, responding more effectively to threats.​

2. Modulates Inflammatory Responses​

Inflammation is a natural immune response that helps the body fight infection and repair tissue. However, chronic or excessive inflammation can weaken the immune system over time, making it less effective at combating pathogens. Pomegranate peel extract contains compounds that help modulate the inflammatory response, ensuring it remains balanced.​

Ellagitannins and flavonoids in the extract inhibit the production of pro-inflammatory molecules, such as cytokines and prostaglandins, which can trigger excessive inflammation. At the same time, they support the production of anti-inflammatory molecules, helping to resolve inflammation once the threat has passed.​

This balanced approach to inflammation is crucial for immune health. By preventing chronic inflammation, pomegranate peel extract helps preserve the immune system’s energy and resources for when they are most needed—fighting off infections.​

3. Supports Gut Microbiome Balance​

The gut microbiome, a complex community of bacteria in the digestive tract, plays a central role in immune function. Approximately 70% of the body’s immune cells are located in the gut, and a healthy balance of beneficial bacteria is essential for training these cells to distinguish between harmful pathogens and harmless substances.​

Pomegranate peel extract may support gut microbiome health in several ways. The ellagitannins in the extract are not fully absorbed in the small intestine, reaching the colon where they act as prebiotics—feeding beneficial bacteria like Lactobacillus and Bifidobacterium. These bacteria ferment the ellagitannins, producing short-chain fatty acids (SCFAs) that support the integrity of the gut lining and promote immune cell development.​

A healthy gut lining acts as a barrier, preventing harmful pathogens from entering the bloodstream and triggering immune responses. By supporting gut microbiome balance and gut barrier function, pomegranate peel extract indirectly enhances overall immune function.​

4. Boosts Immune Cell Activity​

Immune cells, such as macrophages, neutrophils, and lymphocytes, are the body’s first line of defense against pathogens. Pomegranate peel extract has been shown to enhance the activity and production of these cells, strengthening the immune response.​

• Macrophages: These cells engulf and destroy pathogens. Studies suggest that ellagitannins in pomegranate peel extract stimulate macrophage activity, increasing their ability to “eat” and eliminate harmful invaders.​

• Lymphocytes: T cells and B cells are lymphocytes that play key roles in adaptive immunity, remembering pathogens and mounting targeted responses. Research indicates that pomegranate peel compounds may support the proliferation of T cells and enhance the production of antibodies by B cells.​

• Neutrophils: These are the most abundant immune cells, rapidly responding to infections. Pomegranate peel extract may increase neutrophil activity, helping to clear infections more quickly.​

By boosting the function of these cells, pomegranate peel extract enhances the immune system’s ability to detect, attack, and eliminate pathogens.​

5. Supports Mucosal Immunity​

Mucosal surfaces—such as those in the respiratory tract, gut, and nasal passages—are the body’s first physical barriers against pathogens. These surfaces are lined with mucus and immune cells that trap and neutralize invaders before they can enter the body. Pomegranate peel extract may support mucosal immunity by strengthening these barriers.​

Tannins in the extract have astringent properties that help tighten mucosal tissues, reducing their permeability to pathogens. Additionally, the antioxidants in the extract protect mucosal cells from oxidative damage, ensuring they remain healthy and functional.​

For example, in the respiratory tract, a strong mucosal barrier helps prevent viruses and bacteria from entering the lungs. By supporting mucosal immunity, pomegranate peel extract may reduce the risk of respiratory infections and other illnesses caused by pathogens entering through these surfaces.​

Research and Evidence​

While traditional medicine has long used pomegranate peel to support health, modern research is increasingly validating its immune-supporting potential.​

A 2016 study published in Journal of Medicinal Food found that pomegranate peel extract enhanced the activity of macrophages and increased the production of cytokines involved in immune responses in laboratory settings. Another study, published in Phytotherapy Research in 2018, noted that ellagitannins from pomegranate peel promoted the proliferation of T cells and B cells in animal models, improving their ability to fight off infections.​

Human studies are limited but promising. A small 2020 trial involving healthy adults found that daily supplementation with pomegranate peel extract for four weeks increased levels of natural killer (NK) cells—immune cells that target virus-infected cells—compared to a placebo group. Participants also reported fewer cold symptoms during the study period.​

While more large-scale human studies are needed, the existing research suggests that pomegranate peel extract can enhance various aspects of immune function, particularly when combined with a healthy lifestyle.​

How to Choose and Use Pomegranate peel extract supplement

To maximize immune-supporting benefits, it’s important to select high-quality Pomegranate peel extract supplement. Look for products that:​

• Are made from organic pomegranate peels to avoid pesticides and contaminants.​

• Specify the concentration of key compounds, such as ellagitannins (aim for 40–60% purity).​

• Have been third-party tested for quality and potency.​

• Are formulated in forms that enhance absorption, such as capsules with liposomal delivery or tablets with enteric coating.​

Dosage recommendations vary, but most studies use 500–1000 mg of pomegranate peel extract per day. It’s best to take the supplement with a meal containing healthy fats, as many of its compounds are fat-soluble and absorb better with dietary lipids.​

As with any supplement, consult a healthcare provider before starting, especially if you are pregnant, nursing, taking medication, or have a pre-existing condition. Some people may experience mild digestive upset, such as bloating or diarrhea, at higher doses, so starting with a lower dose and gradually increasing may be advisable.

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FAQ

Q1:What about your standard delivery time?

A: For sample orders less than 25kgs, the delivery is within 3 days. For bulk order normally the delivery time is 7-10 days. For urgent order pls kindly double check with our sales before orders confirmed.

Q2:Is there any discount?

A:Sure, Prices are closely related to the quantity. The more, the cheaper.

Q3:Can you provide samples?

A:Yes, normally we can provide FREE samples 5-20 g based on shipping cost at customer’s account.

Q4:Do you have guarantee on your products?

A:The product are 100% pure natural with high quality. We are sure that every batch comes with the unique COA. All extracts are tested in-house; random extracts are tested by authoritative analytical labs.

Q5: What is your MOQ?

A: For most of the products the MOQ is 1kg. But for some of the products we can accept less quantity such as 100g.

Q6: What’s your payment terms?

A: Payment terms such as T/T, Visa Card, Master Card, e-Checking, Paypal, Western Union and Alibaba Trade Assurance are all workable. 2023 New batch Maca Root Extract Powder Nutritious Top grade Maca Extract Powder

Q7:How to ship and delivery?

A: For sample order we always ship via express such as DHL,UPS,TNT, FEDEX, EMS. For bulk orders, air or sea shipment is common.

Q8:Can you supply OEM or ODM service?

A: For sure as is known Ciyuan Biotechnology is specially on producing herb extract; OEM tables, capsules and small packing. For Sure we are the best partner of OEM&ODM supplier.